Trifluoroacetic Acid

Optima™ LC/MS Grade, Fisher Chemical

Chemical Identifiers

CAS 76-05-1
Molecular Formula C2HF3O2
Molecular Weight (g/mol) 114.023
MDL Number 4169
InChI Key DTQVDTLACAAQTR-UHFFFAOYSA-N
Synonym TFA
PubChem CID 6422
ChEBI CHEBI:45892
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Description

  • Ideal high purity mobile phase additive for LC/MS and UHPLC-UV applications
  • Evaluated for metal impurities at ppb concentrations for minimal metal mass adduct formation
  • Screened for UV-absorbing contaminants to reduce interferences and for smoother baselines
  • TFA is a common mobile phase additive that can function as an ion pair reagent

Specifications

0.003 AU max. at 254nm, 0.03 AU max. at 300nm, 0.06 AU max. at 230nm, 0.06 AU max. at 275nm, 0.18 AU max. at 220nm, 0.55 AU max. at 210nm
76-05-1
20 ppb max.
50 ppb max.
≥99.5 %
C2HF3O2
4169
TFA
10 ppb max.
C(=O)(C(F)(F)F)O
114.023
CHEBI:45892
Liquid
Pass Test
10 ppb max.
10 ppb max.
10 ppb max.
20 ppb max.
10 ppb max.
Report ppm
0.05% max.
3.9
0.45
72°C
Trifluoroacetic Acid
Vapor Pressure: 107mbar at 25°C; Vapor Density: 3.9
Optima™ LC/MS
≥99.5%
Report ppm
CF3COOH
15, 9847
1.535g/cm³
DTQVDTLACAAQTR-UHFFFAOYSA-N
2,2,2-trifluoroacetic acid
6422
114.02
Report ppm
10 ppb max.
Pass Test
10 ppb max.
Ampule
1ppm max.
50 ppb max.
107mbar 25
20 ppb max.
-15°C
Colorless
0.5mL

Safety and Handling

Product Identifier

  • TRIFLUOROACETIC ACID


Signal Word

  • Danger


Hazard Category

  • Skin corrosion/irritation Category 1 A
  • Serious eye damage/eye irritation Category 1
  • Acute toxicity Category 4
  • LONG-TERM AQUATIC HAZARD Chronic 3


Hazard Statement

  • H314-Causes severe skin burns and eye damage.
  • H332-Harmful if inhaled.
  • H412-Harmful to aquatic life with long lasting effects.


Precautionary Statement

  • P280-Wear protective gloves/protective clothing/eye protection/face protection.
  • P301+P330+P331-IF SWALLOWED: rinse mouth. Do NOT induce vomiting.
  • P304+P340-IF INHALED: Remove person to fresh air and keep comfortable for breathing.
  • P305+P351+P338-IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing.
  • P310-Immediately call a POISON CENTER/doctor/.
  • P273-Avoid release to the environment.

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